KMID : 1123920180320040291
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Korean Journal of Oriental Physiology and Pathology 2018 Volume.32 No. 4 p.291 ~ p.297
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Pilot Clinical Trial to Evaluate the Efficacy of Needle-Embedding Acupuncture Therapy at Gokji(LI11) on TEWL
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Lee Ho-Chan
Jeong Mi-Young Choi Jeong-Hwa Jung Min-Young Park Soo-Yeon
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Abstract
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The purpose of pilot clinical trial is to evaluate the efiicacy and safety of Needle-Embedding acupuncture therapy on TEWL(Transepidermal Water Loss) and Skin hydration. A total of 24 human who visited Dongshin Oriental Medical Center from December 1st, 2016 to July 31st, 2017 were included in the pilot clinical trial. Needle-Embedding acupuncture therapy performed at Gokji(LI11). We observed change of TEWL(Transepidermal Water Loss), Skin hydration before and after Needle-Embedding acupuncture therapy. In the primary endpoint, index of TEWL showed a statistically insignificant decline (8.5¡¾2.12¡æ7.8¡¾1.53 g/h/m2). Index of skin hydration showed a statistically significant result (38.2¡¾6.77¡æ36.8¡¾6.64). To evaluate the safety, Adverse events and Vital sign check were conducted and there were no problem. And when the physical response, self-awareness, skin system, musculoskeletal pain, and other abnormal responses were assessed 60 minutes and 24 hours and 7 days after Needle-Embedding acupuncture therapy at Gokji(LI11) for stability assessment, Adverse events disappeared during a pilot clinical trial. According to the above pilot clinical trial, it is suggested Needle-Embedding acupuncture therapy were effective for Skin moisturizing and safe.
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KEYWORD
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Needle-Embedding acupuncture therapy, Pilot clinical trial, TEWL(Transepidermal Water Loss), Safety, Gokji (LI11)
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